Rapid Endovascular Catheter Core Cooling Combined With Cold Saline as an Adjunct to€Percutaneous Coronary Intervention for the€Treatment of Acute Myocardial Infarction

Rapid Endovascular Catheter Core Cooling Combined With Cold Saline as an Adjunct to Percutaneous Coronary Intervention for the Treatment of Acute Myocardial Infarction The CHILL-MI Trial: A Randomized Controlled Study of the Use of Central Venous Catheter Core Cooling Combined With Cold Saline as an Adjunct to Percutaneous Coronary Intervention for the Treatment of Acute Myocardial Infarction David Erlinge, MD, PHD,* Matthias Götberg, MD, PHD,* Irene Lang, MD, PHD,y Michael Holzer, MD, PHD,y Marko Noc, MD, PHD,z Peter Clemmensen, MD, PHD,x Ulf Jensen, MD, PHD,jj Bernhard Metzler, MD, PHD,{ Stefan James, MD, PHD,#** Hans Erik Bötker, MD, PHD,yy Elmir Omerovic, MD, PHD,yy Henrik Engblom, MD, PHD,zz Marcus Carlsson, MD, PHD,zz Håkan Arheden, MD, PHD,zz Ollie Östlund, MSC,# Lars Wallentin, MD, PHD,#** Jan Harnek, MD, PHD,* Göran K. Olivecrona, MD, PHD* Lund, Stockholm, Uppsala, and Gothenburg, Sweden; Vienna and Innsbruck, Austria; Ljubljana, Slovenia; and Copenhagen, Denmark